three online databases (ExoCarta, Vesiclepedia and EVpedia). For each database, the pro-teins found in exosomes were collected and a list of proteins/corresponding genes present was produced for each bioﬂuid. The ﬁnal bioﬂuid proteome lists also include proteins

To benefit the scientific community, existing free Web-based resources including ExoCarta, EVpedia, and Vesiclepedia catalog multiple datasets. These resources aid in elucidating molecular mechanism and pathophysiology underlying different disease conditions from which EVs are isolated.

Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication An overall comparison of EVpedia with Exocarta and Vesiclepedia is shown in Tables I and II. These three web‐based repositories contain proteomic, transcriptomic and lipidomic studies of non‐mammalian eukaryotic and mammalian EVs. However, only EVpedia provides additional proteomic and lipidomic studies on prokaryotic EVs (Table I). Exosomal proteomes derived from CSF, serum and plasma were obtained by accessing three online databases (ExoCarta, Vesiclepedia and EVpedia). For each database, the proteins found in exosomes were collected and a list of proteins/corresponding genes present was produced for each biofluid. To benefit the scientific community, existing free Web-based resources including ExoCarta, EVpedia, and Vesiclepedia catalog multiple datasets. These resources aid in elucidating molecular mechanism and pathophysiology underlying different disease conditions from which EVs are isolated. three online databases (ExoCarta, Vesiclepedia and EVpedia).

With the launch of Vesiclepedia, we expect to have an organised data deposition mechanism. Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, Exosomes (30-140 nm) and larger microvesicles [MVs] (100-1000 nm) are subcategories of extracellular vesicles that are released into the circulation. Exosomes contain peptides and several nucleic acids (microRNA [miRNA], messenger RNA [mRNA], mitochondrial DNA [mtDNA]) and are involved in intercellular/tissue exchange of their contents. An overall comparison of EVpedia with Exocarta and Vesiclepedia is shown in Tables I and II. These three web‐based repositories contain proteomic, transcriptomic and lipidomic studies of non‐mammalian eukaryotic and mammalian EVs. However, only EVpedia provides additional proteomic and lipidomic studies on prokaryotic EVs (Table I). As sources of gene product annotations in the exRNA context, ExoCarta [ 45] and Vesiclepedia [ 46] are online databases that catalogue proteins, RNAs and lipids identified specifically in exosomes and other extracellular vesicle types, respectively.

In addition, we have initiated an ongoing process of extractions of gene product annotations associated with these terms from Vesiclepedia and ExoCarta,

Recent studies have ignited significant interest on EVs by elucidating their role in intercellular communication, Exosomes are membranous vesicles that are released by a variety of cells into the extracellular microenvironment and are implicated in intercellular communication. As exosomes contain RNA, proteins and lipids, there is a significant interest in characterizing the molecular cargo of exosomes.

Gene product annotations extracted from ExoCarta and Vesiclepedia. At the time of writing this manuscript, 18,695 coding (mRNA and protein) and 963 non-coding (ncRNAs) gene products (including isoforms) were annotated with the GO terms: ‘extracellular vesicle’, ‘extracellular exosome’, ‘apoptotic body’ and ‘microvesicle’ identified in different species (Table 2) from ExoCarta

(Figure 2) shows statistics and exosome databases like Exocarta (http://www.exocarta.org/) and Vesiclepedia (http://microvesicles.org/) to identify target proteins for focused annotation 16 Apr 2012 Keywords: exosome resource; microvesicle database; exosome tools; extracellular organelles; Vesiclepedia. Received: 10 March 2012; Revised: Among these 35 proteins, 33 proteins were detected in the ExoCarta/ Vesiclepedia database, and 15 of them were identified in the ovarian cancer cell lines We have also assessed the overlap of the proteins in our data set with publicly available EV protein databases ExoCarta, Vesiclepedia, and EVpedia [21], [22], 3 Sep 2019 Vesiclepedia (Version 3.1, 2017) and Exocarta (July 2015) were downloaded to map previously reported EV proteins. Gene ontology (GO) ExoCarta is a manually curated database of exosomal proteins,RNA and lipids. Year founded: 2009. Last update: 2015. Version: v1.0.

This report represents a current and Some articles were collected from two publicly available resources, ExoCarta and Vesiclepedia , which are two manually curated databases specialized in collecting information on extracellular vesicles.
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Vesiclepedia: The Extracellular Vesicles Database 2of14 BADHWARET AL. Inthelastdecadeorso,EVs,particularlybrain-secretedEVs(BEVs) isolatedfrombloodhaveemergedasanovelplayerinAlzheimer’sdis-ease (AD) progression In addition, we have initiated an ongoing process of extractions of gene product annotations associated with these terms from Vesiclepedia and ExoCarta, conversion of the extracted annotations to In addition, we have initiated an ongoing process of extractions of gene product annotations associated with these terms from Vesiclepedia and ExoCarta, conversion of the extracted annotations to Gene Association File (GAF) format for batch submission to GO, and curation of the submitted annotations by the GO Consortium. 2016-04-12 · Of the 519 mass spectrometry identifications, 517 were used for this analysis as there were two sets of proteins for which a single gene name was used by the Exocarta and Vesiclepedia databases to Analytic tools in EVpedia, Exocarta, and Vesiclepedia. Fig. 2.

Described initially in 2009 [32], the database has been visited by more than 16,000 unique users [33]. However, only exosomal studies (as reported by the authors) are catalogued in ExoCarta.
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On Monday and Tuesday April 19–20, 2021, the ERCC hosted a free online workshop on exRNA data analysis. There were three target audiences: experimentalists generating exRNA-seq data, computational and data scientists who have worked with those groups to analyze their data, and other interested data scientists.

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2016-01-01 · ExoCarta collects data from five species (Homo sapiens, Rattus norvegicus, Mus musculus, Ovis aries, and Cavia porcellus) and 52 samples. All the data can be downloaded from the download web page of the database. 5.3. Vesiclepedia: The Extracellular Vesicles Database

Here we 7 Jun 2019 The data were extracted from the Exocarta, Vesiclepedia, UniProt, Open Target, DisGeNET, and Atlas databases. The majority of the proteins pathways, we used the SecretomeP 2.0 prediction server.

Proteomics characterization of human PROSPR-CNS-EVs. a Venn diagram of EV proteins matched to records in the EV databases Exocarta [], Vesiclepedia [] and EVpedia [].Of the total 2901 proteins identified, 61.8 % were associated with exosome markers and cargoes, 75.4 % were associated with microvesicle markers and cargoes and 23.6 % were novel identifications in brain EVs. Some articles were collected from two publicly available resources, ExoCarta and Vesiclepedia , which are two manually curated databases specialized in collecting information on extracellular vesicles. 2019-05-28 · Dublin, May 28, 2019 (GLOBE NEWSWIRE) -- The "Exosome Diagnostics and Therapeutics: Global Markets" report has been added to ResearchAndMarkets.com's offering. This report represents a current and In this article, we discuss the utility of ExoCarta for exosomal research and urge biomedical researchers in the field to deposit their datasets directly to ExoCarta. Vesiclepedia -- a compendium for extracellular vesicles with continuous community annotation. We compared all the proteins identified in our study to those known vesicular proteins in the Exocarta (38, 39) and Vesiclepedia databases (40, 41).